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Article

Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer

1 Jun 2013

Abstract excerpt

Breast cancer is a heterogeneous tumor type characterized by a complex spectrum of molecular aberrations, resulting in a diverse array of malignant features and clinical outcomes. Deciphering the molecular mechanisms that fuel breast cancer development and act as determinants of aggressiveness is a primary need to improve patient management. Among other alterations, aberrant expression of microRNAs has been found...

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PMID: 23656790
DOI: 10.4161/cc.24757

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