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Article

Preferential Protection of Genetic Fidelity within Open Chromatin by the Mismatch Repair Machinery.

The Journal of biological chemistry - 19 Aug 2016

Sun Lue, Zhang Yan, Zhang Zhuqiang, Zheng Yong, Du Lilin, Zhu Bing

Abstract excerpt

Epigenetic systems are well known for the roles they play in regulating the differential expression of the same genome in different cell types. However, epigenetic systems can also directly impact genomic integrity by protecting genetic sequences. Using an experimental evolutionary approach, we studied rates of mutation in the fission yeast Schizosaccharomyces pombe strains that lacked genes encoding several...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27382058
DOI: 10.1074/jbc.M116.719971
PMCID: PMC5016164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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