Article
The Spontaneous Mutation Rate in the Fission Yeast Schizosaccharomyces pombe.
Genetics - 1 Oct 2015
Farlow Ashley, Long Hongan, Arnoux Stéphanie, Sung Way, Doak Thomas G, Nordborg Magnus, Lynch Michael
Abstract excerpt
The rate at which new mutations arise in the genome is a key factor in the evolution and adaptation of species. Here we describe the rate and spectrum of spontaneous mutations for the fission yeast Schizosaccharomyces pombe, a key model organism with many similarities to higher eukaryotes. We undertook an ∼1700-generation mutation accumulation (MA) experiment with a haploid S. pombe, generating 422 single-base...
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