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Article

Evolutionary pressures on microbial metabolic strategies in the chemostat.

Scientific reports - 6 Jul 2016

Wortel Meike T, Bosdriesz Evert, Teusink Bas, Bruggeman Frank J

Abstract excerpt

Protein expression is shaped by evolutionary processes that tune microbial fitness. The limited biosynthetic capacity of a cell constrains protein expression and forces the cell to carefully manage its protein economy. In a chemostat, the physiology of the cell feeds back on the growth conditions, hindering intuitive understanding of how changes in protein concentration affect fitness. Here, we aim to provide a...

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Identifiers

PMID: 27381431
DOI: 10.1038/srep29503
PMCID: PMC4933952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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