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Article

A genome-scale metabolic model of Saccharomyces cerevisiae that integrates expression constraints and reaction thermodynamics.

Nature communications - 9 Aug 2021

Oftadeh Omid, Salvy Pierre, Masid Maria, Curvat Maxime, Miskovic Ljubisa, Hatzimanikatis Vassily

Abstract excerpt

Eukaryotic organisms play an important role in industrial biotechnology, from the production of fuels and commodity chemicals to therapeutic proteins. To optimize these industrial systems, a mathematical approach can be used to integrate the description of multiple biological networks into a single model for cell analysis and engineering. One of the most accurate models of biological systems include Expression...

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Identifiers

PMID: 34373465
DOI: 10.1038/s41467-021-25158-6
PMCID: PMC8352978

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