Article
Suboptimal resource allocation in changing environments constrains response and growth in bacteria.
Molecular systems biology - 1 Dec 2021
Balakrishnan Rohan, de Silva Roshali T, Hwa Terence, Cremer Jonas
Abstract excerpt
To respond to fluctuating conditions, microbes typically need to synthesize novel proteins. As this synthesis relies on sufficient biosynthetic precursors, microbes must devise effective response strategies to manage depleting precursors. To better understand these strategies, we investigate the active response of Escherichia coli to changes in nutrient conditions, connecting transient gene expression to growth...
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