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Article

Action potential broadening in a presynaptic channelopathy.

Nature communications - 6 Jul 2016

Begum Rahima, Bakiri Yamina, Volynski Kirill E, Kullmann Dimitri M

Abstract excerpt

Brain development and interictal function are unaffected in many paroxysmal neurological channelopathies, possibly explained by homoeostatic plasticity of synaptic transmission. Episodic ataxia type 1 is caused by missense mutations of the potassium channel Kv1.1, which is abundantly expressed in the terminals of cerebellar basket cells. Presynaptic action potentials of small inhibitory terminals have not been...

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Identifiers

PMID: 27381274
DOI: 10.1038/ncomms12102
PMCID: PMC4935806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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