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Article

Mutations in the G-domain of Ski7 cause specific dysfunction in non-stop decay.

Scientific reports - 6 Jul 2016

Horikawa Wataru, Endo Kei, Wada Miki, Ito Koichi

Abstract excerpt

Ski7 functions as a cofactor in both normal mRNA turnover and non-stop mRNA decay (NSD) mRNA surveillance in budding yeast. The N-terminal region of Ski7 (Ski7N) interacts with the ski-complex and the exosome. The C-terminal region of Ski7 (Ski7C) binds guanine nucleotides and shares overall sequence and structural homology with the proteins of the translational GTPase superfamily, especially the tRNA/tRNA-mimic...

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Identifiers

PMID: 27381255
DOI: 10.1038/srep29295
PMCID: PMC4933942

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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