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Article

Context-dependent dual role of SKI8 homologs in mRNA synthesis and turnover.

PLoS genetics - 1 Jan 2012

Dorcey Eavan, Rodriguez-Villalon Antia, Salinas Paula, Santuari Luca, Pradervand Sylvain, Harshman Keith, Hardtke Christian S

Abstract excerpt

Eukaryotic mRNA transcription and turnover is controlled by an enzymatic machinery that includes RNA polymerase II and the 3' to 5' exosome. The activity of these protein complexes is modulated by additional factors, such as the nuclear RNA polymerase II-associated factor 1 (Paf1c) and the cytoplasmic Superkiller (SKI) complex, respectively. Their components are conserved across uni- as well as multi-cellular...

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Identifiers

PMID: 22511887
DOI: 10.1371/journal.pgen.1002652
PMCID: PMC3325215

Genes

SKI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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