Article
A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women.
Breast cancer research : BCR - 5 Jun 2018
Bensen Jeannette T, Graff Mariaelisa, Young Kristin L, Sethupathy Praveen, Parker Joel, Pecot Chad V, Currin Kevin, Haddad Stephen A, Ruiz-Narváez Edward A, Haiman Christopher A, Hong Chi-Chen, Sucheston-Campbell Lara E, Zhu Qianqian, Liu Song, Yao Song, Bandera Elisa V, Rosenberg Lynn, Lunetta Kathryn L, Ambrosone Christine B, Palmer Julie R, Troester Melissa A, Olshan Andrew F
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) regulate gene expression and influence cancer. Primary transcripts of miRNAs (pri-miRNAs) are poorly annotated and little is known about the role of germline variation in miRNA genes and breast cancer (BC). We sought to identify germline miRNA variants associated with BC risk and tumor subtype among African-American (AA) women. METHODS: Under the African American Breast Cancer...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.