Article
Global population-specific variation in miRNA associated with cancer risk and clinical biomarkers.
BMC medical genomics - 28 Aug 2014
Rawlings-Goss Renata A, Campbell Michael C, Tishkoff Sarah A
Abstract excerpt
BACKGROUND: MiRNA expression profiling is being actively investigated as a clinical biomarker and diagnostic tool to detect multiple cancer types and stages as well as other complex diseases. Initial investigations, however, have not comprehensively taken into account genetic variability affecting miRNA expression and/or function in populations of different ethnic backgrounds. Therefore, more complete surveys of...
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