Article
Common genetic polymorphisms of microRNA biogenesis pathway genes and risk of breast cancer: a case-control study in Korea.
Breast cancer research and treatment - 1 Dec 2011
Sung Hyuna, Lee Kyoung-Mu, Choi Ji-Yeob, Han Sohee, Lee Ji-Young, Li Lian, Park Sue K, Yoo Keun-Young, Noh Dong-Young, Ahn Sei-Hyun, Kang Daehee
Abstract excerpt
Recent compelling evidence indicates that mutation, aberrant expression, and dysregulation of microRNA (miRNA) biogenesis are implicated in cancer development and progression. Based on the important role of miRNA biogenesis pathway in carcinogenesis, we hypothesized that genetic variations in this pathway genes may play a role as susceptibility factors for breast cancer. To test this hypothesis, we investigated...
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