Identification of diagnostic and prognostic biomarkers for cancer: Focusing on genetic variations in microRNA regulatory pathways (Review).

Abstract excerpt

MicroRNAs (miRNAs) are a highly conserved class of small, noncoding RNAs, which regulate gene expression by post‑transcriptional degradation or translational repression. miRNAs are involved in the regulation of cell apoptosis, proliferation, differentiation and other physiological processes. They have been increasingly recognized to be involved in the initiation and progression of human carcinogenesis. More...

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