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Article

Identification and Functional Characterization of RSPO2 as a Susceptibility Gene for Ossification of the Posterior Longitudinal Ligament of the Spine.

American journal of human genetics - 7 Jul 2016

Nakajima Masahiro, Kou Ikuyo, Ohashi Hirofumi, Ikegawa Shiro

Abstract excerpt

Ossification of the posterior longitudinal ligament of the spine (OPLL) is a common spinal disorder that results from ectopic ossification of the posterior longitudinal ligament and causes intractable myelopathy and radiculopathy. In a previous genome-wide association study (GWAS), we found six loci associated with OPLL; however, susceptibility genes in these loci have not been identified yet. Here, we examined...

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Source

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Identifiers

PMID: 27374772
DOI: 10.1016/j.ajhg.2016.05.018
PMCID: PMC5005442

Genes

RSPO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification and Functional Characterization of RSPO2 as a Susceptibility Gene for Ossification of the Posterior Longitudinal Ligament of the Spine.PMID 27374772Read ↗

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