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Genetic insights into ossification of the posterior longitudinal ligament of the spine

16 Jun 2023

Abstract excerpt

Ossification of the posterior longitudinal ligament of the spine (OPLL) is an intractable disease leading to severe neurological deficits. Its etiology and pathogenesis are primarily unknown. The relationship between OPLL and comorbidities, especially type 2 diabetes (T2D) and high body mass index (BMI), has been the focus of attention; however, no trait has been proven to have a causal relationship. We conducted...

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PMID: 37461309
DOI: 10.7554/elife.86514

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Genetic insights into ossification of the posterior longitudinal ligament of the spinePMID 37461309Read ↗

Genetic insights into ossification of the posterior longitudinal ligament of the spineSemantic proximity Read ↗

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Genomewide linkage and linkage disequilibrium analyses identify COL6A1, on chromosome 21, as the locus for ossification of the posterior longitudinal ligament of the spine.Semantic proximity Read ↗

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