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Article

Integrated microRNA-mRNA analyses reveal OPLL specific microRNA regulatory network using high-throughput sequencing

12 Feb 2016

Abstract excerpt

Ossification of the posterior longitudinal ligament (OPLL) is a genetic disorder which involves pathological heterotopic ossification of the spinal ligaments. Although studies have identified several genes that correlated with OPLL, the underlying regulation network is far from clear. Through small RNA sequencing, we compared the microRNA expressions of primary posterior longitudinal ligament cells form OPLL...

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PMID: 26868491
DOI: 10.1038/srep21580

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