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Article

β-MSCs: successful fusion of MSCs with β-cells results in a β-cell like phenotype.

Oncotarget - 2 Aug 2016

Azizi Zahra, Lange Claudia, Paroni Federico, Ardestani Amin, Meyer Anke, Wu Yonghua, Zander Axel R, Westenfelder Christof, Maedler Kathrin

Abstract excerpt

Bone marrow mesenchymal stromal cells (MSC) have anti-inflammatory, anti-apoptotic and immunosuppressive properties and are a potent source for cell therapy. Cell fusion has been proposed for rapid generation of functional new reprogrammed cells. In this study, we aimed to establish a fusion protocol of bone marrow-derived human MSCs with the rat beta-cell line (INS-1E) as well as human isolated pancreatic islets...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27374092
DOI: 10.18632/oncotarget.10214
PMCID: PMC5226484

Genes

MSC
INS
PDX1
MAFA
NEUROD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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