Article
Human marrow-derived mesodermal progenitor cells generate insulin-secreting islet-like clusters in vivo.
Stem cells and development - 1 Oct 2007
Ai Cuiwei, Todorov Ivan, Slovak Marilyn L, Digiusto David, Forman Stephen J, Shih Chu-Chih
Abstract excerpt
Transplantation of pancreatic islet cells is the only known potential cure for diabetes mellitus. However, the difficulty in obtaining sufficient numbers of purified islets for transplantation severely limits its use. A renewable and clinically accessible source of stem cells capable of differentiating into insulin-secreting beta-cells might circumvent this limitation. Here, we report that human fetal bone marrow...
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