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Article

Reprogramming mouse embryo fibroblasts to functional islets without genetic manipulation.

Journal of cellular physiology - 1 Feb 2018

Chandravanshi Bhawna, Bhonde Ramesh

Abstract excerpt

The constant quest for generation of large number of islets aimed us to explore the differentiation potential of mouse embryo fibroblast cells. Mouse embryo fibroblast cells isolated from 12- to 14-day-old pregnant mice were characterized for their surface markers and tri-lineage differentiation potential. They were subjected to serum-free media containing a cocktail of islet differentiating reagents and analyzed...

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Source

Identifiers

PMID: 28657136
DOI: 10.1002/jcp.26068

Genes

MSC
PDX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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