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Article

Impact of active smoking on survival of patients with metastatic lung adenocarcinoma harboring an epidermal growth factor receptor (EGFR) mutation.

Bosnian journal of basic medical sciences - 10 Nov 2016

Erdogan Bulent, Kodaz Hilmi, Karabulut Senem, Cinkaya Ahmet, Tozkir Hilmi, Tanriverdi Ozgur, Cabuk Devrim, Hacioglu Muhammed Bekir, Turkmen Esma, Hacibekiroglu Ilhan, Uzunoglu Sernaz, Cicin Irfan

Abstract excerpt

Lung cancer in smokers and non-smokers demonstrates distinct genetic profiles, and cigarette smoking affects epidermal growth factor receptor (EGFR) function and causes secondary EGFR tyrosine kinase resistance. We evaluated the effect of active smoking in patients with metastatic lung adenocarcinoma. A total of 132 metastatic lung adenocarcinoma patients, diagnosed between 2008 and 2013, with known EGFR mutation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27371767
DOI: 10.17305/bjbms.2016.1380
PMCID: PMC5136764

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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