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Article

Impact of heavy smoking on the benefits from first-line EGFR-TKI therapy in patients with advanced lung adenocarcinoma.

Medicine - 1 Mar 2018

Zhang Ping, Nie Xin, Bie Zhixin, Li Lin

Abstract excerpt

Smoking is a risk factor for nonsmall cell lung carcinoma (NSCLC) and is associated with a lower response to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKI). The purpose of this study is to examine the impact of the smoking status on the benefits from first-line EGFR-TKI in NSCLC patients with EGFR mutation.This was a retrospective study of 159 patients with advanced NSCLC treated at the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29489642
DOI: 10.1097/MD.0000000000010006
PMCID: PMC5851738

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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