Article
Impact of Smoking and Brain Metastasis on Outcomes of Advanced EGFR Mutation Lung Adenocarcinoma Patients Treated with First Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors.
PloS one - 1 Jan 2015
Jain Amit, Lim Cindy, Gan Eugene MingJin, Ng David Zhihao, Ng Quan Sing, Ang Mei Kim, Takano Angela, Chan Kian Sing, Tan Wu Meng, Kanesvaran Ravindran, Toh Chee Keong, Loo Chian Min, Hsu Anne Ann Ling, Devanand Anantham, Lim Chong Hee, Koong Heng Nung, Koh Tina, Fong Kam Weng, Yap Swee Peng, Kim Su Woon, Chowbay Balram, Oon Lynette, Lim Kiat Hon, Lim Wan Teck, Tan Eng Huat, Tan Daniel Shao Weng
Abstract excerpt
OBJECTIVES: This purpose of this study was to examine clinical-pathologic factors--particularly smoking and brain metastases--in EGFR mutation positive (M(+)) lung adenocarcinoma (ADC) to determine their impact on survival in patients treated with first line EGFR TKI. METHODS: A retrospective rev...
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