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Article

Impact of smoking status on EGFR-TKI efficacy for advanced non-small-cell lung cancer in EGFR mutants: a meta-analysis.

Clinical lung cancer - 1 Mar 2015

Zhang Yaxiong, Kang Shiyang, Fang Wenfeng, Hong Shaodong, Liang Wenhua, Yan Yue, Qin Tao, Tang Yanna, Sheng Jin, Zhang Li

Abstract excerpt

BACKGROUND: The strong association between smoking history and the presence of epidermal growth factor receptor (EGFR) mutations has been proven in non-small-cell lung cancer (NSCLC), which explains the favorable response to EGFR-tyrosine kinase inhibitor (EGFR-TKI) therapy in nonsmoking NSCLC patients. However, few studies directly focus on the relationship between EGFR-TKI's efficacy and smoking history in...

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Source

Identifiers

PMID: 25454007
DOI: 10.1016/j.cllc.2014.09.008

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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