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Article

Additive sex-specific influence of common non-synonymous DISC1 variants on amygdala, basal ganglia, and white cortical surface area in healthy young adults.

Brain structure & function - 1 Mar 2017

Mühle Christiane, Kreczi Jakob, Rhein Cosima, Richter-Schmidinger Tanja, Alexopoulos Panagiotis, Doerfler Arnd, Lenz Bernd, Kornhuber Johannes

Abstract excerpt

The disrupted-in-schizophrenia-1 (DISC1) gene is known for its role in the development of mental disorders. It is also involved in neurodevelopment, cognition, and memory. To investigate the association between DISC1 variants and brain morphology, we analyzed the influence of the three common non-synonymous polymorphisms in DISC1 on specific brain structures in healthy young adults. The volumes of brain regions...

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PMID: 27369464
DOI: 10.1007/s00429-016-1253-6

Genes

DISC1

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