Article
RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases.
Annals of surgery - 1 Oct 2013
Vauthey Jean-Nicolas, Zimmitti Giuseppe, Kopetz Scott E, Shindoh Junichi, Chen Su S, Andreou Andreas, Curley Steven A, Aloia Thomas A, Maru Dipen M
Abstract excerpt
OBJECTIVE: To determine the impact of RAS mutation status on survival and patterns of recurrence in patients undergoing curative resection of colorectal liver metastases (CLM) after preoperative modern chemotherapy. BACKGROUND: RAS mutation has been reported to be associated with aggressive tumor biology. However, the effect of RAS mutation on survival and patterns of recurrence after resection of CLM remains...
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