Article
Variants in ACPP are associated with cerebrospinal fluid Prostatic Acid Phosphatase levels.
BMC genomics - 29 Jun 2016
Staley Lyndsay A, Ebbert Mark T W, Bunker Daniel, Bailey Matthew, Ridge Perry G, Goate Alison M, Kauwe John S K
Abstract excerpt
BACKGROUND: Prostatic Acid Phosphatase (PAP) is an enzyme that is produced primarily in the prostate and functions as a cell growth regulator and potential tumor suppressor. Understanding the genetic regulation of this enzyme is important because PAP plays an important role in prostate cancer and is expressed in other tissues such as the brain. METHODS: We tested association between 5.8 M SNPs and PAP levels in...
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