Article
[Estrogen resistance and aromatase deficiency in humans].
Journal de la Societe de biologie - 1 Jan 2002
Carani Cesare, Fabbi Matteo, Zirilli Lucia, Sgarbi Ilaria
Abstract excerpt
The primordial role of estrogens in female reproductive function is well known. The recent production of transgenic mice deficient in estrogen receptors (ERKO) or in aromatase (ArKO) and the discovery in man of inactivating mutations of the corresponding genes (ER) have contributed to the understanding of the role of estrogens in metabolic processes in female as well as male. To date 8 well documented cases (5...
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