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Article

The Human Bcl-2 Family Member Bcl-rambo Localizes to Mitochondria and Induces Apoptosis and Morphological Aberrations in Drosophila.

PloS one - 1 Jan 2016

Nakazawa Mako, Matsubara Hisanori, Matsushita Yuka, Watanabe Megumi, Vo Nicole, Yoshida Hideki, Yamaguchi Masamitsu, Kataoka Takao

Abstract excerpt

Bcl-2 family proteins play a central role in regulating apoptosis. We previously reported that human Bcl-rambo, also termed BCL2L13, localized to mitochondria and induced apoptosis when overexpressed in human embryonic kidney 293T cells. However, the physiological function of Bcl-rambo currently remains unclear. In the present study, human Bcl-rambo was ectopically expressed in Drosophila melanogaster. Bcl-rambo...

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Identifiers

PMID: 27348811
DOI: 10.1371/journal.pone.0157823
PMCID: PMC4922555

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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