Article
Apoptosis in Drosophila: which role for mitochondria?
Apoptosis : an international journal on programmed cell death - 1 Mar 2016
Clavier Amandine, Rincheval-Arnold Aurore, Colin Jessie, Mignotte Bernard, Guénal Isabelle
Abstract excerpt
It is now well established that the mitochondrion is a central regulator of mammalian cell apoptosis. However, the importance of this organelle in non-mammalian apoptosis has long been regarded as minor, mainly because of the absence of a crucial role for cytochrome c in caspase activation. Recent results indicate that the control of caspase activation and cell death in Drosophila occurs at the mitochondrial...
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