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HLA-Cw6 allele, NFkB1 and NFkBIA polymorphisms play no role in predicting response to etanercept in psoriatic patients.

Pharmacogenetics and genomics - 1 Sept 2016

Caldarola Giacomo, Sgambato Alessandro, Fanali Caterina, Moretta Gaia, Farina Marisa, Lucchetti Donatella, Peris Ketty, De Simone Clara

Abstract excerpt

OBJECTIVE: This retrospective study aimed to evaluate the role of NFKB1-94 insertion/deletion ATTG (rs28362491) and NFkBIA 2758 A>G (rs696) polymorphisms and HLA-Cw6 allele in predicting the response to etanercept, a TNF-α blocker, in a population of psoriatic patients naive to biologics. METHODS: Genomic DNA was extracted from whole blood in a series of 96 psoriatic patients who received etanercept for at least...

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Source

Identifiers

PMID: 27348478
DOI: 10.1097/FPC.0000000000000233

Genes

NFKB1
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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