Article
Role of the HLA-C*06 allele in clinical response to ustekinumab: evidence from real life in a large cohort of European patients.
The British journal of dermatology - 1 Aug 2017
Talamonti M, Galluzzo M, van den Reek J M, de Jong E M, Lambert J L W, Malagoli P, Bianchi L, Costanzo A
Abstract excerpt
BACKGROUND: Little is known about the role of the HLA-C*06 allele in the response to psoriasis treatments. OBJECTIVES: To confirm the role of HLA-C*06 as a pharmacogenetic marker of response to ustekinumab in a new, large cohort of patients involving four European centres. METHODS: In this retrospective multicentre study we reviewed data of 255 patients with psoriasis genotyped for HLA-C*06 who started...
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