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Article

Intraflagellar transport is required for the maintenance of the trypanosome flagellum composition but not its length.

Journal of cell science - 1 Aug 2016

Fort Cécile, Bonnefoy Serge, Kohl Linda, Bastin Philippe

Abstract excerpt

Intraflagellar transport (IFT) is required for construction of most cilia and flagella. Here, we used electron microscopy, immunofluorescence and live video microscopy to show that IFT is absent or arrested in the mature flagellum of Trypanosoma brucei upon RNA interference (RNAi)-mediated knockdown of IFT88 and IFT140, respectively. Flagella assembled prior to RNAi did not shorten, showing that IFT is not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27343245
DOI: 10.1242/jcs.188227

Genes

IFT88

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Intraflagellar transport is required for the maintenance of the trypanosome flagellum composition but not its length.PMID 27343245Read ↗

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