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Article

Dependency relationships between IFT-dependent flagellum elongation and cell morphogenesis in Leishmania

1 Nov 2018

Abstract excerpt

Flagella have multiple functions that are associated with different axonemal structures. Motile flagella typically have a 9 + 2 arrangement of microtubules, whereas sensory flagella normally have a 9 + 0 arrangement. Leishmania exhibits both of these flagellum forms and differentiation between these two flagellum forms is associated with cytoskeletal and cell shape changes. We disrupted flagellum elongation in...

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PMID: 30463910
DOI: 10.1098/rsob.180124

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