Article
Functional genomics in Trypanosoma brucei identifies evolutionarily conserved components of motile flagella.
Journal of cell science - 1 Feb 2007
Baron Desiree M, Ralston Katherine S, Kabututu Zakayi P, Hill Kent L
Abstract excerpt
Cilia and flagella are highly conserved, complex organelles involved in a variety of important functions. Flagella are required for motility of several human pathogens and ciliary defects lead to a variety of fatal and debilitating human diseases. Many of the major structural components of cilia and flagella are known, but little is known about regulation of flagellar beat. Trypanosoma brucei, the causative agent...
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