Article
A novel function for the atypical small G protein Rab-like 5 in the assembly of the trypanosome flagellum.
Journal of cell science - 15 Mar 2009
Adhiambo Christine, Blisnick Thierry, Toutirais Géraldine, Delannoy Emmanuelle, Bastin Philippe
Abstract excerpt
The atypical small G protein Rab-like 5 has been shown to traffic in sensory cilia of Caenorhabditis elegans, where it participates in signalling processes but not in cilia construction. In this report, we demonstrate that RABL5 colocalises with intraflagellar transport (IFT) proteins at the basal body and in the flagellum matrix of the protist Trypanosoma brucei. RABL5 fused to GFP exhibits anterograde movement...
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