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Article

Gene copy number alteration profile and its clinical correlation in B-cell acute lymphoblastic leukemia.

Leukemia & lymphoma - 1 Feb 2017

Gupta Sanjeev Kumar, Bakhshi Sameer, Kumar Lalit, Kamal Vineet Kumar, Kumar Rajive

Abstract excerpt

The genes related to B-cell development are frequently altered in B-cell acute lymphoblastic leukemia (B-ALL). One hundred sixty-two newly diagnosed B-ALL cases, median age 8.5 years (2 months-67 years), were prospectively analyzed for copy number alterations (CNAs) in CDKN2A/B, IKZF1, PAX5, RB1, ETV6, BTG1, EBF1, and pseudoautosomal region genes (CRLF2, CSF2RA, IL3RA) using multiplex ligation-dependent probe...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27339065
DOI: 10.1080/10428194.2016.1193855

Genes

IKZF1
PAX5
BTG1
CRLF2
EBF1
ETV6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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