Article
Prognostic utility of key copy number alterations in T cell acute lymphoblastic leukemia.
Hematological oncology - 1 Oct 2022
Kumari Sarita, Ali M Shadab, Singh Jay, Arora Mohit, Verma Deepak, Pandey Avanish Kumar, Benjamin Mercilena, Bakhshi Sameer, Palanichamy Jayanth Kumar, Sharma Atul, Singh Inder, Tanwar Pranay, Singh Amar Ranjan, Pushpam Deepam, Qamar Imteyaz, Chopra Anita
Abstract excerpt
T-cell acute lymphoblastic leukemia (T-ALL) is a genetically heterogeneous disease, characterized by an abnormal transformation of T cells into highly proliferative leukemic lymphoblasts. Identification of common genetic alterations has provided promising opportunities for better risk stratification in T-ALL. Current treatment in T-ALL still poses the major challenge of integrating the knowledge of molecular...
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