Back to search

Article

Prognostic impact of copy number alterations in pediatric B-cell precursor acute lymphoblastic leukemia: A collaborative data from two major oncology centers of North India

2022-05-19

Abstract excerpt

<title>Abstract</title> <p>In current study, copy number alteration (CNA) status and CNA risk profiles of IKZF1plus, UK-ALL CNA risk groups and MRplus score, were evaluated for clinical and prognostic impact in a cohort of 493 B-ALL cases diagnosed and treated under ICICLE trial at two major oncology centres of Northern India. Overall CNA frequency was 59% with 60% of cases showing 2-loci deletion. CDKN2A/B delet...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
22bde9f0-eeda-555c-83f8-ff4174dc2c06
DOI
10.21203/rs.3.rs-1663909/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Prognostic impact of copy number alterations in pediatric B-cell precursor acute lymphoblastic leukemia: A collaborative data from two major oncology centers of North IndiaDOI 10.21203/rs.3.rs-1663909/v1
Copy number alterations in B-cell development genes, drug resistance, and clinical outcome in pediatric B-cell precursor acute lymphoblastic leukemiaSemantic proximity
The clinical impact of IKZF1 deletions in paediatric B-cell precursor acute lymphoblastic leukaemia is independent of minimal residual disease stratification in Nordic Society for Paediatric Haematology and Oncology treatment protocols used between 1992 and 2013.Semantic proximity
Prognostic significance of copy number alterations in adolescent and adult patients with precursor B acute lymphoblastic leukemia enrolled in PETHEMA protocolsSemantic proximity
Quantitative analysis of IKZF1 gene deletions in pediatric B-cell precursor acute lymphoblastic leukemia: Higher levels are associated with a poorer prognosisSemantic proximity
Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes.Semantic proximity
Quantitative analysis of IKZF1 gene deletions in pediatric B-cell precursor acute lymphoblastic leukemia: Higher levels are associated with a poorer prognosisSemantic proximity
Prognostic impact of chromosomal abnormalities and copy number alterations in adult B-cell precursor acute lymphoblastic leukaemia: a UKALL14 studySemantic proximity
Childhood Acute B-Lineage Lymphoblastic Leukemia With CDKN2A/B Deletion Is a Distinct Entity With Adverse Genetic Features and Poor Clinical OutcomesSemantic proximity
Heterogeneity of IKZF1 genomic alterations and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemiaSemantic proximity
IKZF1 Gene in Childhood B-cell Precursor Acute Lymphoblastic Leukemia: Interplay between Genetic Susceptibility and Somatic Abnormalities.Semantic proximity
DNA Copy Number Alterations and Copy Neutral Loss of Heterozygosity in Adult Ph-Negative Acute B-Lymphoblastic Leukemia: Focus on the Genes InvolvedSemantic proximity
Gene copy number alteration profile and its clinical correlation in B-cell acute lymphoblastic leukemia.Semantic proximity
Select a neighboring publication to make it the new centre.