Article
QuIN: A Web Server for Querying and Visualizing Chromatin Interaction Networks.
PLoS computational biology - 1 Jun 2016
Thibodeau Asa, Márquez Eladio J, Luo Oscar, Ruan Yijun, Menghi Francesca, Shin Dong-Guk, Stitzel Michael L, Vera-Licona Paola, Ucar Duygu
Abstract excerpt
UNLABELLED: Recent studies of the human genome have indicated that regulatory elements (e.g. promoters and enhancers) at distal genomic locations can interact with each other via chromatin folding and affect gene expression levels. Genomic technologies for mapping interactions between DNA regions, e.g., ChIA-PET and HiC, can generate genome-wide maps of interactions between regulatory elements. These interaction...
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