Article
HiView: an integrative genome browser to leverage Hi-C results for the interpretation of GWAS variants.
BMC research notes - 11 Mar 2016
Xu Zheng, Zhang Guosheng, Duan Qing, Chai Shengjie, Zhang Baqun, Wu Cong, Jin Fulai, Yue Feng, Li Yun, Hu Ming
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with complex traits and diseases. However, most of them are located in the non-protein coding regions, and therefore it is challenging to hypothesize the functions of these non-coding GWAS variants. Recent large efforts such as the ENCODE and Roadmap Epigenomics projects have predicted a large number of...
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