Epilogos: information-theoretic navigation of multi-tissue functional genomic annotations

Abstract excerpt

Functional genomics data, such as chromatin state maps, provide critical insights into biological processes, but are hard to navigate and interpret. We present Epilogos to address this challenge by offering a simple information-theoretic framework for large-scale visualization, navigation and interpretation of functional genomics annotations, and apply it to over 2,000 genome-wide chromatin state maps in human and...

Topics

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• Breast Neoplasms
• Computational Biology
• Data Analysis
• Databases, Genetic
• Gene Expression Profiling
• Genome, Human
• Phenotype
• Transcriptome

Identifiers and source

Literature Corpus work

3e263d7e-4ace-5c12-a9be-47761b66b39e

DOI

10.1101/2025.06.18.660301