Article

A novel genetic mouse model of fatal aortic dissection reveals massive inflammatory cell infiltration in the thoracic aorta

2024-05-07

Abstract excerpt

<h4>Background</h4> Aortic dissection (AD) is the separation of medial layers of the aorta and is a major cause of death in patients with connective tissue disorders such as Marfan syndrome. However, molecular triggers instigating AD, its temporospatial progression, and how vascular cells in each vessel layer interact and participate in the pathological process remain incompletely understood. To unravel the under...

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Literature Corpus work: 82f55e29-04c0-5ccf-8fef-1a0a84b3a2fe
DOI: 10.1101/2024.05.02.592287

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