Article
Transcriptional Truncation of the Long Coding Imprinted Gene Usp29.
PloS one - 1 Jan 2016
He Hongzhi, Ye An, Kim Joomyeong
Abstract excerpt
Usp29 (Ubiquitin-specific protease 29) is a paternally expressed gene located upstream of another imprinted gene Peg3. In the current study, the transcription of this long coding gene spanning a 250-kb genomic distance was truncated using a knockin allele. According to the results, paternal transmission of the mutant allele resulted in reduced body and litter sizes whereas the maternal transmission caused no...
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