Article
Microsatellite in the 3' untranslated region of human fibroblast growth factor 9 (FGF9) gene exhibits pleiotropic effect on modulating FGF9 protein expression.
Human mutation - 1 Jan 2007
Chen Tsung-Ming, Kuo Pao-Lin, Hsu Chien-Hui, Tsai Shaw-Jenq, Chen Mong-Jen, Lin Chieh-Wei, Sun H Sunny
Abstract excerpt
Fibroblast growth factor 9 (FGF9) is a member of secreted polypeptide families and involved in many important biological processes, including implantation and morphogenesis during embryogenesis and adult life. Recently, Fgf9-knockout mice exhibited male-to-female sex reversal, demonstrating a novel function for FGF9 in testicular development. We hypothesized that FGF9 is involved in sex development at an early...
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