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Article

Drosophila polypyrimidine tract-binding protein (DmPTB) regulates dorso-ventral patterning genes in embryos.

PloS one - 1 Jan 2014

Heimiller Joseph, Sridharan Vinod, Huntley Jim, Wesley Cedric S, Singh Ravinder

Abstract excerpt

The Drosophila polypyrimidine tract-binding protein (dmPTB or hephaestus) plays an important role during embryogenesis. A loss of function mutation, heph(03429), results in varied defects in embryonic developmental processes, leading to embryonic lethality. However, the suite of molecular functions that are disrupted in the mutant remains unknown. We have used an unbiased high throughput sequencing approach to...

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Identifiers

PMID: 25014769
DOI: 10.1371/journal.pone.0098585
PMCID: PMC4094481

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