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Article

Transcription-driven DNA methylation setting on the mouse Peg3 locus.

Epigenetics - 1 Jan 2017

Bretz Corey L, Kim Joomyeong

Abstract excerpt

The imprinting of the mouse Peg3 domain is controlled through the Peg3-DMR, which obtains its maternal-specific DNA methylation during oogenesis. In the current study, we deleted an oocyte-specific alternative promoter, termed U1, which is localized 20 kb upstream of the Peg3-DMR. Deletion of this alternative promoter resulted in complete removal of the maternal-specific DNA methylation on the Peg3-DMR....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomic Imprinting

Share to Kruppel-Like Transcription Factors

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Source

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Identifiers

PMID: 28925797
DOI: 10.1080/15592294.2017.1377869
PMCID: PMC5788428

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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