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Article

Cholesterol Metabolism and Prostate Cancer Lethality

21 Jun 2016

Abstract excerpt

Cholesterol metabolism has been implicated in prostate cancer pathogenesis. Here, we assessed the association of intratumoral mRNA expression of cholesterol synthesis enzymes, transporters, and regulators in tumor specimen at diagnosis and lethal prostate cancer, defined as mortality or metastases from prostate cancer in contrast to nonlethal disease without evidence of metastases after at least 8 years of...

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PMID: 27325648
DOI: 10.1158/0008-5472.can-16-0903

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