Article

Cholesterol Synthesis Pathway Genes in Prostate Cancer are consistently downregulated when tissue confounding is minimized

2017-11-17

Abstract excerpt

The relationship between cholesterol and prostate cancer has been extensively studied for decades, where high levels of cellular cholesterol are generally associated with cancer progression and less favorable outcomes. However, the role of in vivo cellular cholesterol synthesis in this process is unclear, and data on the transcriptional activity of cholesterol synthesis pathway genes in tissue from prostate cancer...

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Identifiers and source

Literature Corpus work: 16e01a5a-84f5-5288-a0fe-44a744504484
DOI: 10.1101/220400

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