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Article

Mutant p53 Gain of Function and Chemoresistance: The Role of Mutant p53 in Response to Clinical Chemotherapy.

Chemotherapy - 1 Jan 2017

He Chao, Li Lun, Guan Xuan, Xiong Li, Miao Xiongying

Abstract excerpt

PURPOSE: To review mechanisms underlying mutant p53 (mutp53) gain of function (GOF) and mutp53-induced chemoresistance, and to investigate the role of mutp53 in response to clinical chemotherapy. METHODS: We searched the PubMed database for clinical studies from the past decade, including data evaluating the impact of mutp53 in clinical chemotherapy response. RESULTS: Interactions between mutp53 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27322648
DOI: 10.1159/000446361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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