Article
Alterations of circulating lymphoid committed progenitor cellular metabolism after allogeneic stem cell transplantation in humans.
Experimental hematology - 1 Sept 2016
Glauzy Salomé, Peffault de Latour Régis, André-Schmutz Isabelle, Lachuer Joël, Servais Sophie, Socié Gérard, Clave Emmanuel, Toubert Antoine
Abstract excerpt
Lymphoid-committed CD34(+)lin(-)CD10(+)CD24(-) progenitors undergo a rebound at month 3 after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in the absence of acute graft-versus-host disease (aGVHD). Here, we analyzed transcriptional programs of cell-sorted circulating lymphoid-committed progenitors and CD34(+)Lin(-)CD10(-) nonlymphoid progenitors in 11 allo-HSCT patients who had (n = 5) or had...
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